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Encapsulation of copigmented anthocyanins within polysaccharide microcapsules built upon removable CaCO 3 templates
Food Hydrocolloids ( IF 11.0 ) Pub Date : 2018-11-01 , DOI: 10.1016/j.foodhyd.2018.05.036
Chen Tan , Michael Joseph Selig , Michelle C. Lee , Alireza Abbaspourrad

Abstract This work fabricated natural polysaccharide-based polyelectrolyte microcapsules via layer-by-layer assembly (LBL) as carriers for copigmented anthocyanins. For this purpose, the chondroitin sulfate (CHS)/anthocyanin copigmented complexes were coprecipitated into spherical templates created by formation of CaCO3 precipitates. This template complex formation is then followed by deposition of oppositely charged CHS and chitosan (CS), and subsequent dissolution of CaCO3 core. We found that copigmentation with CHS of moderate concentration increased the encapsulation efficiency of anthocyanin in CaCO3, favored anthocyanin retention in the microcapsule and improved the prolonged release of anthocyanin in a simulated gastrointestinal environment. The mechanism behind these observations was hypothesized to be related to the decreased micropolarity and microviscosity in the matrix-type interior of hybrid microcapsules. These results strongly support the combined use of polyelectrolyte microencapsulation and copigmentation techniques for the development of novel systems targeting the stabilization and controlled release of water-soluble molecules such as the anthocyanins studied herein.

中文翻译:

在可移动 CaCO 3 模板上构建的多糖微胶囊中封装共染色的花青素

摘要 本工作通过逐层组装 (LBL) 制备了天然多糖基聚电解质微胶囊,作为复合花青素的载体。为此,硫酸软骨素 (CHS)/花青素复合物共沉淀成由 CaCO3 沉淀形成的球形模板。这种模板复合物的形成之后是带相反电荷的 CHS 和壳聚糖 (CS) 的沉积,随后是 CaCO3 核的溶解。我们发现,与中等浓度的 CHS 共染色提高了花青素在 CaCO3 中的包封效率,有利于花青素在微胶囊中的保留,并改善了花青素在模拟胃肠环境中的延长释放。假设这些观察结果背后的机制与混合微胶囊基质型内部的微极性和微粘度降低有关。这些结果强烈支持聚电解质微囊化和共着色技术的联合使用,以开发针对水溶性分子(如本文研究的花青素)的稳定和受控释放的新型系统。
更新日期:2018-11-01
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