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N‐Heterocyclic Carbene‐Catalyzed Annulation of Ylides with Ynals: Direct Access to α‐Pyrones
Chemistry - An Asian Journal ( IF 4.1 ) Pub Date : 2018-06-19 , DOI: 10.1002/asia.201800595
Ming Lang 1 , Qianfa Jia 1 , Jian Wang 1
Affiliation  

We herein report an N‐Heterocyclic Carbene (NHC)‐catalyzed annulation of ylides with ynals that provides an efficient protocol to make 4,6‐disubstituted α‐pyrones. This method affords a variety of α‐pyrones in good to high yields as well as broad substrate scope and good functional group tolerance.

中文翻译:

带有Ynals的Y环的N杂环碳环催化环空:直接获得α-Pyrones

我们在此报告了N-杂环卡宾(NHC)催化的带有芳基的酰基化物环化,提供了制备4,6-二取代的α-吡喃酮的有效方法。该方法可提供高产率到高产率的各种α-吡喃酮,以及广泛的底物范围和良好的官能团耐受性。
更新日期:2018-06-19
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