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Association of Comorbidities With Adverse Outcomes After Enterostomy Closure in Premature Neonates
JAMA Surgery ( IF 15.7 ) Pub Date : 2018-08-01 , DOI: 10.1001/jamasurg.2018.0880
Donald J. Lucas 1 , Ankush Gosain 1, 2
Affiliation  

Surgical emergencies in premature neonates, such as necrotizing enterocolitis, spontaneous intestinal perforation, intestinal obstruction, complicated gastroschisis, and malrotation with volvulus, are often treated with bowel resection and enterostomy, leading to complications such as infection, stricture, liver disease, impaired growth, and developmental delay.1-3 Enterostomy closure has been shown to improve weight gain in most neonates.3 Many institutions choose arbitrary weight targets of 2.0 to 2.5 kg at closure to minimize postoperative complications.4,5 We sought to determine the safety of enterostomy closure in premature neonates weighing less than 2 kg and to identify risk factors for adverse outcomes.



中文翻译:

早产儿肠造口闭合后合并症与不良结果的关联

早产儿的外科手术急症,如坏死性小肠结肠炎,自发性肠穿孔,肠梗阻,复杂性胃气管病和肠扭转,通常需行肠切除和肠造口术治疗,导致并发症如感染,狭窄,肝病,生长障碍,和发展的延迟。1 -3肠造口术的闭合已显示可改善大多数新生儿的体重增加。3许多机构在闭合时选择2.0至2.5 kg的任意重量目标,以最大程度地减少术后并发症。4 ,5我们试图确定肠造口闭合的早产儿体重小于2kg的安全,并确定不良后果的危险因素。

更新日期:2018-08-15
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