Water-soluble, carbazole-based two-photon excitable fluorescent probes MPVC-I (“turn-on”) and MPVC-II (“turn-off”) are rationally designed and synthesized for the selective monitoring of carbon monoxide (CO). Both probes can effectively measure carboxyhemoglobin (HbCO) in the blood of the animals exposed to a CO dose as low as 100 ppm for 10 min. The palladium catalyzed azidocarbonylation reaction was optimized to improve the sensing efficiency.

中文翻译：

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开启和关闭荧光探针，用于一氧化碳检测和血液中的碳氧血红蛋白测定

水溶性，咔唑基双光子可激发荧光探针MPVC-I（“开启”）和MPVC-II（“关闭”）经过合理设计和合成，用于选择性监测一氧化碳（CO）。两种探针都可以有效地测量暴露于低至100 ppm的CO剂量下10分钟的动物血液中的羧基血红蛋白（HbCO）。优化了钯催化的叠氮羰基化反应以提高感测效率。