Environmental pollution by pharmaceutically active compounds, used in quantities similar to those of pesticides and other organic micropollutants, is increasingly recognized as a major threat to the aquatic environment. These compounds are only partly removed from wastewaters and, despite their low concentrations, directly and indirectly affect behaviour of freshwater organisms in natural habitats. The aim of this study was to behaviourally assess the effects of an opioid painkiller (tramadol) and antidepressant drug (citalopram) on behaviour patterns of a clonal model species, marbled crayfish. Animals exposed to environmentally relevant concentrations of both tested compounds (∼1 μg l⁻¹) exhibited significantly lower velocity and shorter distance moved than controls. Crayfish exposed to tramadol spent more time in shelters. Results were obtained by a simple and rapid method recommended as suitable for assessment of behaviour in aquatic organisms exposed to single pollutants and combinations.

越来越多地认为，药用活性化合物对环境的污染与农药和其他有机微污染物的用量相似，已成为对水生环境的主要威胁。这些化合物仅从废水中部分除去，尽管它们的浓度很低，但它们直接或间接地影响了自然栖息地中淡水生物的行为。这项研究的目的是通过行为评估阿片类镇痛药（曲马多）和抗抑郁药（西酞普兰）对克隆模型物种大理石纹小龙虾行为模式的影响。暴露于两种测试化合物的环境相关浓度的动物（〜1μgl ^-1）的速度明显低于对照组，移动距离更短。暴露于曲马多的小龙虾在避难所里度过了更多的时间。通过简单而快速的方法获得了结果，推荐该方法适合评估暴露于单一污染物及其组合的水生生物的行为。