Recent Developments in the C(sp3)−H Functionalization of 2‐Oxindoles through Radical Reactions,Asian Journal of Organic Chemistry

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Recent Developments in the C(sp3)−H Functionalization of 2‐Oxindoles through Radical Reactions
Asian Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2018-06-07 , DOI: 10.1002/ajoc.201800209
Wei-Ting Chen ₁ , Wen-Ting Wei ₁

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3‐Substituted 2‐oxindoles are prevalent in a variety of natural products and bioactive compounds. As such, the synthesis of these molecules is highly desirable. This Focus Review provides a critical overview of recent developments (in particular, reports since 2013) in the C(sp³)−H functionalization of 2‐oxindoles through radical reactions. The main achievements in this field are presented according to the bonds that are formed. Special attention is paid to the reaction mechanisms, and a personal outlook on future developments in this research area is provided.

中文翻译：

通过自由基反应的2-Oxindoles C（sp3）-H功能化的最新进展

在各种天然产物和生物活性化合物中普遍使用3-取代的2-吲哚。这样，这些分子的合成是非常合乎需要的。本重点综述提供了对通过自由基反应在2-氧吲哚的C（sp ³）-H功能化方面的最新进展（尤其是2013年以来的报告）的重要概述。根据已形成的纽带，介绍了该领域的主要成就。特别注意反应机制，并对本研究领域的未来发展提供了个人见解。

更新日期：2018-06-07

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