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Synthesis of Sub‐100 nm Glycosylated Nanoparticles via a One Step, Free Radical, and Surfactant Free Emulsion Polymerization
Macromolecular Rapid Communications ( IF 4.2 ) Pub Date : 2018-05-02 , DOI: 10.1002/marc.201800122 Andrew M Lunn 1 , Sébastien Perrier 1, 2, 3
Macromolecular Rapid Communications ( IF 4.2 ) Pub Date : 2018-05-02 , DOI: 10.1002/marc.201800122 Andrew M Lunn 1 , Sébastien Perrier 1, 2, 3
Affiliation
The facile synthesis of sub‐100 nm glyco nanoparticles is presented via a one‐step, free radical, and surfactant free emulsion polymerization. It is shown that by using sterically large, hydrophilic glycomonomers such as a lactose acrylamide with the charged azo initiator 4,4′‐azobis(4‐cyanovaleric acid), growing particles are stabilized enough to reproducibly produce well defined (PDi ≤ 0.1) glycoparticles with diameters below 100 nm.
中文翻译:
通过一步、自由基、无表面活性剂乳液聚合合成亚 100 nm 糖基化纳米颗粒
通过一步、自由基和无表面活性剂的乳液聚合,可以轻松合成亚 100 nm 糖纳米颗粒。结果表明,通过使用空间大的亲水性糖单体,例如乳糖丙烯酰胺和带电偶氮引发剂 4,4'-偶氮双(4-氰基戊酸),生长的颗粒足够稳定,可以重复地产生明确的(PDi ≤ 0.1)糖颗粒直径小于100 nm。
更新日期:2018-05-02
中文翻译:
通过一步、自由基、无表面活性剂乳液聚合合成亚 100 nm 糖基化纳米颗粒
通过一步、自由基和无表面活性剂的乳液聚合,可以轻松合成亚 100 nm 糖纳米颗粒。结果表明,通过使用空间大的亲水性糖单体,例如乳糖丙烯酰胺和带电偶氮引发剂 4,4'-偶氮双(4-氰基戊酸),生长的颗粒足够稳定,可以重复地产生明确的(PDi ≤ 0.1)糖颗粒直径小于100 nm。