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A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas†
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2018-05-11 00:00:00 , DOI: 10.1039/c8qo00338f
Hugo Santalla 1, 2, 3, 4, 5 , Fátima Garrido 1, 2, 3, 4, 5 , Generosa Gómez 1, 2, 3, 4, 5 , Yagamare Fall 1, 2, 3, 4, 5
Affiliation  

After a serendipitous synthesis of a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas, a more reliable synthetic method is now described using our building blocks containing stereodefined stereochemistry at C-20.

中文翻译:

Gemini维生素D类似物的更可靠合成,这是一种潜在有效的治疗结肠直肠癌的化学治疗剂

在偶然合成了可能有效的大肠癌治疗药物后,现在使用我们在C-20上包含立体定义立体化学的结构单元,描述一种更可靠的合成方法。
更新日期:2018-05-11
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