Taking enantiomers for a spin There are two common ways to distinguish mirror-image molecules, or enantiomers. The first relies on their distinct interactions with circularly polarized light, the second on their interactions with a pure enantiomer of some other molecule. Now Banerjee-Ghosh et al. report a conceptually different approach to chiral resolution. Experiments showed that, depending on the direction of magnetization, chiral oligopeptides, oligonucleotides, and amino acids have enantiospecific differences in initial adsorption rates on ferromagnetic surfaces. This effect is attributed to enantiospecific induced spin polarization. Science, this issue p. 1331 Spin polarization of chiral molecules enhances the initial adsorption rate of one enantiomer onto a ferromagnetic substrate. It is commonly assumed that recognition and discrimination of chirality, both in nature and in artificial systems, depend solely on spatial effects. However, recent studies have suggested that charge redistribution in chiral molecules manifests an enantiospecific preference in electron spin orientation. We therefore reasoned that the induced spin polarization may affect enantiorecognition through exchange interactions. Here we show experimentally that the interaction of chiral molecules with a perpendicularly magnetized substrate is enantiospecific. Thus, one enantiomer adsorbs preferentially when the magnetic dipole is pointing up, whereas the other adsorbs faster for the opposite alignment of the magnetization. The interaction is not controlled by the magnetic field per se, but rather by the electron spin orientations, and opens prospects for a distinct approach to enantiomeric separations.

中文翻译：

---

通过与非手性磁性底物的对映特异性相互作用分离对映异构体

以对映异构体进行旋转 有两种常见的方法来区分镜像分子或对映异构体。第一个依赖于它们与圆偏振光的独特相互作用，第二个依赖于它们与某些其他分子的纯对映异构体的相互作用。现在 Banerjee-Ghosh 等人。报告了一种概念上不同的手性拆分方法。实验表明，根据磁化方向的不同，手性寡肽、寡核苷酸和氨基酸在铁磁表面上的初始吸附率具有对映特异性差异。这种效应归因于对映特异性诱导的自旋极化。科学，这个问题 p。1331 手性分子的自旋极化提高了一种对映异构体在铁磁基材上的初始吸附率。人们普遍认为，无论是在自然界还是在人工系统中，对手性的识别和辨别都完全取决于空间效应。然而，最近的研究表明，手性分子中的电荷重新分布表现出电子自旋方向的对映特异性偏好。因此，我们推断诱导自旋极化可能通过交换相互作用影响对映识别。在这里，我们通过实验表明手性分子与垂直磁化底物的相互作用是对映特异性的。因此，当磁偶极子朝上时，一种对映体优先吸附，而另一种对映体在磁化方向相反时吸附得更快。相互作用不受磁场本身的控制，而是受电子自旋方向的控制，