Corona discharge ionization sources are often used in ion mobility spectrometers (IMS) when a non-radioactive ion source with high ion currents is required. Typically, the corona discharge is followed by a reaction region where analyte ions are formed from the reactant ions. In this work, we present a simple yet sufficiently accurate model for predicting the ion current available at the end of this reaction region when operating at reduced pressure as in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) or most IMS-MS instruments. It yields excellent qualitative agreement with measurement results and is even able to calculate the ion current within an error of 15%. Additional interesting findings of this model are the ion current at the end of the reaction region being independent from the ion current generated by the corona discharge and the ion current in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) growing quadratically when scaling down the length of the reaction region.

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当需要具有高离子电流的非放射性离子源时，电晕放电电离源通常用于离子迁移谱仪 (IMS)。通常，电晕放电之后是反应区，其中由反应物离子形成分析物离子。在这项工作中，我们提出了一个简单但足够准确的模型，用于预测在高动能离子迁移谱仪 (HiKE-IMS) 或大多数 IMS-MS 仪器中在减压下操作时该反应区域末端可用的离子电流。它与测量结果具有极好的定性一致性，甚至能够在 15% 的误差内计算离子电流。

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