The United States Preventive Services Task Force (USPSTF) is the most widely regarded source for information on US cancer screening. In 2012, the USPSTF gave prostate cancer screening a grade “D” recommendation, essentially guiding physicians and patients to discourage prostate cancer early detection.¹ This recommendation may have had an adverse effect on prostate cancer incidence rates across risk groups, including potentially lethal cancers, and was widely decried by specialty and advocacy groups.² The grade D recommendation was based on what is now known to be an incorrect interpretation of the clinical evidence supporting screening at the time and legitimate concerns about cancer overdetection and overtreatment (the detection and treatment of indolent cancers that would not have been a problem if left undiagnosed and untreated).

美国预防服务工作队（USPSTF）是有关美国癌症筛查信息的最广泛来源。2012年，USPSTF为前列腺癌筛查提供了“ D”级推荐，从根本上指导医生和患者劝阻前列腺癌的早期发现。¹该建议可能会对包括潜在致死性癌症在内的所有风险人群的前列腺癌发生率产生不利影响，并且被专业和拥护团体广泛否定。^2个 D级推荐基于目前对当时支持筛查的临床证据的错误解释，以及对癌症过度检测和过度治疗的合理关注（如果保留下来，对惰性癌症的检测和治疗将不成问题）。未诊断和未治疗）。