Assemblies of plasmonic nanoparticles enable new modalities for biosensing. Engineered superstructures from metal nanoparticles can enhance the plasmon resonances and chiroptical activity of nanoscale dispersions. Such phenomena are keys to the fabrication of highly sensitive, selective and fast-responding detection platforms, making them promising candidates for clinical applications. This tutorial review summarizes and discusses recent advances in this area. The topics covered in the review include the basic strategies adopted for assembly and engineering of plasmonic nanoparticles, optical properties of the assembled nanostructures and their applications to both in vitro and in vivo detection of biological compounds. We also offer our vision of the future prospects of this field of research. Among emerging applications in this area are novel nanosensors and platforms, for food safety, environmental monitoring, health safeguarding, as well as biodefense.

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对环境敏感的等离激元纳米组件用于生物传感

等离子体纳米颗粒的组装为生物传感提供了新的形式。由金属纳米颗粒设计的超结构可以增强纳米级分散体的等离子体共振和手性。这种现象是制造高灵敏度，选择性和快速响应的检测平台的关键，使其成为临床应用的有希望的候选者。本教程审查总结并讨论了该领域的最新进展。覆盖在审查的主题包括用于组装和等离子体纳米颗粒，所述组装纳米结构的光学性质和它们的应用程序两者的工程采用的基本策略在体外和体内生物化合物的检测。我们还提供了我们对该研究领域的未来前景的看法。在该领域新兴的应用是用于食品安全，环境监测，健康维护以及生物防御的新型纳米传感器和平台。