Stents are vital devices to treat vascular stenosis in pediatric patients with congenital heart disease. Bioresorbable stents (BRSs) have been applied to reduce challenging complications caused by permanent metal stents. However, it remains almost a total lack of BRSs with satisfactory compression performance specifically for children with congenital heart disease, leading to importantly suboptimal effects. In this work, composite bioresorbable prototype stents with superior compression resistance were designed by braiding and annealing technology, incorporating poly (p-dioxanone) (PPDO) monofilaments and polycaprolactone (PCL) multifilament. Stent prototype compression properties were investigated. The results revealed that novel composite prototype stents showed superior compression force compared to the control ones, as well as recovery ability. Furthermore, deformation mechanisms were analyzed by computational simulation, which revealed bonded interlacing points among yarns play an important role. This research presents important clinical implications in bioresorbable stent manufacture and provides further study with an innovative stent design.

支架是治疗先天性心脏病小儿血管狭窄的重要设备。生物可吸收支架（BRS）已被应用来减少由永久金属支架引起的具有挑战性的并发症。但是，几乎完全没有BRS具有令人满意的抗压性能，特别是针对先天性心脏病的儿童，导致严重的次优效果。在这项工作中，通过编织和退火技术结合了聚（p-二恶烷酮（PPDO）单丝和聚己内酯（PCL）复丝。研究了支架原型的压缩特性。结果表明，新型复合材料原型支架显示出比对照组更好的压缩力以及恢复能力。此外，通过计算机仿真分析了变形机理，结果表明纱线之间的粘合交织点起着重要的作用。这项研究提出了在生物可吸收支架制造中的重要临床意义，并通过创新的支架设计提供了进一步的研究。