Thus far, optical recording of neuronal activity in freely behaving animals has been limited to a thin axial range. We present a head-mounted miniaturized light-field microscope (MiniLFM) capable of capturing neuronal network activity within a volume of 700 × 600 × 360 µm3 at 16 Hz in the hippocampus of freely moving mice. We demonstrate that neurons separated by as little as ~15 µm and at depths up to 360 µm can be discriminated.

中文翻译：

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自由移动啮齿动物中神经元活动的高速体积成像。

迄今为止，自由行为动物中神经元活动的光学记录已被限制在较薄的轴向范围内。我们提出了一种头戴式微型光场显微镜（MiniLFM），它能够捕获自由移动小鼠海马体中700×600×360 µm3，频率为16 Hz时的神经元网络活动。我们证明，可以区分仅约15 µm且深度达360 µm的神经元。