Polycomb repressive complex 2 (PRC2) is a chief epigenetic regulator. In a new article, Chen et al. describe the crystal structure of the heterotetrameric PRC2 holo complex, which provides important mechanistic insights into the organization of its subunits and the association of PRC2 with chromatin.

中文翻译：

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PRC2 Holo建筑群的体系结构

聚梳抑制复合物2（PRC2）是主要的表观遗传调控因子。Chen等人在一篇新文章中。描述了异四聚体PRC2整体复合物的晶体结构，这为深入了解其亚基的组织以及PRC2与染色质的缔合提供了重要的机理见解。