Polyester elastomers for soft tissue engineering,Chemical Society Reviews

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Polyester elastomers for soft tissue engineering
Chemical Society Reviews ( IF 40.4 ) Pub Date : 2018-05-03 00:00:00 , DOI: 10.1039/c8cs00161h
Hongye Ye _{1,

2,

3} , Kangyi Zhang _{1,

2,

3} , Dan Kai _{1,

2,

3} , Zibiao Li _{1,

2,

3} , Xian Jun Loh _{1,

2,

3,

4,

5}

Affiliation

Polyester elastomers are soft, biodegradable and biocompatible and are commonly used in various biomedical applications, especially in tissue engineering. These synthetic polyesters can be easily fabricated using various techniques such as solvent casting, particle leaching, molding, electrospinning, 3-dimensional printing, photolithography, microablation etc. A large proportion of tissue engineering research efforts have focused on the use of allografts, decellularized animal scaffolds or other biological materials as scaffolds, but they face the major concern of triggering immunological responses from the host, on top of other issues. This review paper will introduce the recent developments in elastomeric polyesters, their synthesis and fabrication techniques, as well as their application in the biomedical field, focusing primarily on tissue engineering in ophthalmology, cardiac and vascular systems. Some of the commercial and near-commercial polyesters used in these tissue engineering fields will also be described.

中文翻译：

用于软组织工程的聚酯弹性体

聚酯弹性体柔软，可生物降解且具有生物相容性，通常用于各种生物医学应用中，尤其是在组织工程中。这些合成聚酯可以使用各种技术轻松制造，例如溶剂浇铸，颗粒浸出，成型，静电纺丝，三维印刷，光刻，微烧蚀等。组织工程研究的大部分工作都集中在使用同种异体移植物，脱细胞的动物支架或其他生物材料作为支架上，但除其他问题外，它们还面临引发宿主免疫应答的主要问题。这篇综述文章将介绍弹性体聚酯的最新进展，其合成和制造技术以及它们在生物医学领域的应用，主要侧重于眼科，心脏和血管系统的组织工程。也将描述在这些组织工程领域中使用的一些商业和接近商业的聚酯。

更新日期：2018-05-03

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