A chemical investigation of the ascomycetes of Daldinia concentrica was performed using silica gel column chromatography, ODS column chromatography, and preparative HPLC. Two new isoindolinone compounds, daldinans B (1) and C (2), two new phthalide compounds, daldinolides A (3) and B (4), and a new naphthoquinone, daldiquinone (5), were isolated together with two known compounds (6 and 7). The structures of 1, 2, and 5 were established using NMR, MS, and IR methods, and the structures of 3 and 4 were determined by derivatization from known compounds (6 and 7). 5 exhibited antiangiogenesis activity against HUVECs (IC₅₀ = 7.5 μM).

中文翻译：

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异吲哚啉，苯酞，并从子实体萘Daldinia concentrica

使用硅胶柱色谱，ODS柱色谱和制备型HPLC进行了对Daldiniacentriccentrica子囊菌的化学研究。分离出了两种新的异吲哚啉酮化合物，达迪南B（1）和C（2），两种新的邻苯二甲酸酯化合物，达迪诺内酯A（3）和B（4），以及新的萘醌，daldiquinone（5），以及两种已知的化合物（6和7）。的结构1，2，和5使用NMR，MS和IR方法和的结构建立了3和4通过衍生自已知化合物（6和7）来确定化合物的含量。5表现出针对HUVEC的抗血管生成活性（IC ₅₀ = 7.5μM）。