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Maternal Metabolomic Profile and Fetal Programming of Offspring Adiposity: Identification of Potentially Protective Lipid Metabolites.
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2018-05-28 , DOI: 10.1002/mnfr.201700889
Christian Hellmuth 1 , Karen L Lindsay 2, 3 , Olaf Uhl 1 , Claudia Buss 2, 3, 4 , Pathik D Wadhwa 2, 3, 5 , Berthold Koletzko 1 , Sonja Entringer 3, 4
Affiliation  

The fetal programming paradigm posits that the origins of obesity can be traced, in part, to the intrauterine period of life. However, the mechanisms underlying fetal programming are not well understood, and few studies have measured offspring adiposity in the neonatal period. The aim of this study is to identify maternal metabolites, and their determinants, that are associated with neonatal adiposity.

中文翻译:

孕产妇代谢组学概况和后代肥胖的胎儿编程:潜在的保护性脂质代谢产物的鉴定。

胎儿编程范例认为,肥胖的起源可以部分追溯到子宫内的生命周期。但是,对胎儿编程的机制尚不十分了解,很少有研究测量新生儿期的后代肥胖。这项研究的目的是确定与新生儿肥胖相关的母亲代谢产物及其决定因素。
更新日期:2018-05-28
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