Rationale: Among the biothiols-related diseases, sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection and can result in severe oxidative stress and damage to multiple organs. In this study, we aimed to develop a fluorescence chemosensor that can both detect GSH and further predict sepsis.

中文翻译：

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基于萘的谷胱甘肽荧光探针及其在活细胞和败血症患者中的应用

理由：在与生物硫醇有关的疾病中，败血症定义为威胁生命的器官功能障碍，是由于宿主对感染的反应失调引起的，并可能导致严重的氧化应激和对多个器官的损害。在这项研究中，我们旨在开发一种可以检测GSH并进一步预测败血症的荧光化学传感器。