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D-alanyl-D-alanine-Modified Gold Nanoparticles Form a Broad-Spectrum Sensor for Bacteria
Theranostics ( IF 12.4 ) Pub Date : 2018-02-04 , DOI: 10.7150/thno.22540
Xinglong Yang , Yan Dang , Jinli Lou , Huawu Shao , Xingyu Jiang

Rationale: Rapid and facile detection of pathogenic bacteria is challenging due to the requirement of large-scale instruments and equipment in conventional methods. We utilize D-amino acid as molecules to selectively target bacteria because bacteria can incorporate DADA in its cell wall while mammalian cells or fungi cannot.

中文翻译:

D-丙氨酰-D-丙氨酸修饰的金纳米粒子形成细菌的广谱传感器。

理由:由于常规方法需要大规模的仪器和设备,因此快速,简便地检测病原菌具有挑战性。我们利用D-氨基酸作为分子来选择性地靶向细菌,因为细菌可以在其细胞壁中掺入DADA,而哺乳动物细胞或真菌则不能。
更新日期:2018-05-01
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