Peptide‐Based Nanocarriers for Cancer Therapy,Small Methods

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Peptide‐Based Nanocarriers for Cancer Therapy
Small Methods ( IF 10.7 ) Pub Date : 2018-04-30 , DOI: 10.1002/smtd.201700358
Guoqing Wei ₁ , Yi Wang ₁ , Xuehui Huang ₁ , Huabo Hou ₁ , Shaobing Zhou ₁

Affiliation

Peptides, which are made up of amino acids, are an excellent candidate as a composition component of a nanocarrier for drug delivery due to their biocompatibility, bioavailability, and stability in vivo. Here, the progress in peptides as nanocarriers for applications in cancer therapy are summarized, including as a nanocarrier matrix for self‐assembled nanoparticles, as surface modification moieties of nanocarriers for targeting and/or penetrating function, and as enzyme‐responsive linkers of nanoparticles for triggering drug release. Peptide‐based nanocarriers should receive more attention, and they have great potential in biomedical applications.

中文翻译：

基于肽的纳米载体用于癌症治疗

由氨基酸组成的肽由于其生物相容性，生物利用度和体内稳定性，是作为用于药物递送的纳米载体的组成成分的极好的候选物。在此，总结了肽在癌症治疗中作为纳米载体的应用进展，包括作为自组装纳米颗粒的纳米载体基质，作为靶向和/或穿透功能的纳米载体的表面修饰部分，以及作为纳米颗粒的酶促反应连接物。触发药物释放。基于肽的纳米载体应引起更多关注，它们在生物医学应用中具有巨大的潜力。

更新日期：2018-04-30

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