Self‐Assembled “Breathing” Grana‐Like Cisternae Stacks,Advanced Materials

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Self‐Assembled “Breathing” Grana‐Like Cisternae Stacks
Advanced Materials ( IF 27.4 ) Pub Date : 2018-04-30 , DOI: 10.1002/adma.201707482
Qingchuan Li ₁ , Xiaojun Han ₁

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Membranes in cells display elaborate, dynamic morphologies intimately tied to defined cellular functions. Cisternae stacks are a common membrane morphology in cells widely found in organelles. However, compared with the well‐studied spherical cell membrane mimics, cisternae stacks as organelle membrane mimics are greatly neglected because of the difficulty of fabricating this unique structure. Herein, the grana‐like cisternae stacks are assembled via the reorganization of stacked microsized bicelles to mimic grana functions. The cisternae stacks are connected by fusion regions between adjacent cisternae. The number of cisternae can be controlled from ≈4 to 15 by the variation of ethanol volume percentage. Under the stimulation of solvent or negatively charged nanoparticles, the cisternae stacks can reversibly compress and expand, similar to the “breathing” property of natural grana. During the “breathing” process, nanoparticles are reversibly captured and released. Frequency resonance energy transfer is realized on the cisternae stacks trapped with two kinds of quantum dots. The cisternae stacks provide advanced membrane model for cell biotechnology, and clues for the shaping of organelles composed of cisternae. The ability of the cisternae stacks to capture materials enables them to possibly be applied in biomimetics and the design of advanced functional materials.

中文翻译：

自组装的“呼吸式” Gran-like水箱叠层

细胞中的膜表现出与已定义的细胞功能密切相关的精细的动态形态。池盖堆叠是细胞器中广泛发现的细胞中常见的膜形态。但是，与研究透彻的球形细胞膜模拟物相比，作为细胞器膜模拟物的水箱叠层由于制造这种独特结构的困难而被大大忽略。在此，通过重组堆叠的微型电池仓以模仿谷物功能，组装了类似谷物的水箱。池池堆通过相邻池之间的融合区域连接。通过改变乙醇体积百分比，可以将池中的数控制在≈4至15之间。在溶剂或带负电的纳米粒子的刺激下，水箱叠层可以可逆地压缩和膨胀，类似于天然燕麦的“呼吸”特性。在“呼吸”过程中，可逆地捕获和释放纳米颗粒。在被两种量子点俘获的水箱叠层中实现了共振能量的转移。池池堆为细胞生物技术提供了先进的膜模型，并为由池池组成的细胞器成型提供了线索。水池的叠层捕获材料的能力使它们有可能被应用于仿生品和高级功能材料的设计中。以及塑造由水箱组成的细胞器的线索。水池的叠层捕获材料的能力使它们有可能被应用于仿生品和高级功能材料的设计中。以及塑造由水箱组成的细胞器的线索。水池的叠层捕获材料的能力使它们有可能被应用于仿生品和高级功能材料的设计中。

更新日期：2018-04-30

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