Resveratrol Ameliorates the Severity of Fibrogenesis in Mice with Experimental Chronic Pancreatitis,Molecular Nutrition & Food Research

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Resveratrol Ameliorates the Severity of Fibrogenesis in Mice with Experimental Chronic Pancreatitis
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2018-01-04 , DOI: 10.1002/mnfr.201700561
Yixuan Xia ₁ , Hai-Tao Xiao ₁ , Kanglun Liu ₁ , Hong-Jie Zhang ₁ , Siu Wai Tsang _{1,

2}

Affiliation

Resveratrol is generally considered beneficial to health‐span and longevity since this dietary stilbenoid has been scrutinized for its activating property on the “rescue gene” sirtuin‐1 that promotes cellular survival under stress. In addition to its antiaging property, our previous in vitro studies revealed that resveratrol notably inhibits the production of extracellular matrix (ECM) proteins in pancreatic stellate cells (PSCs), the classic effector cells against pancreatic injury.

中文翻译：

白藜芦醇改善实验性慢性胰腺炎小鼠纤维化的严重程度。

白藜芦醇通常被认为有益于健康和长寿，因为这种饮食中的类胡萝卜素已因其对“拯救基因” sirtuin-1的激活特性而被仔细研究，该sirtuin-1在压力下促进细胞存活。除了其抗衰老性能外，我们先前的体外研究表明，白藜芦醇可显着抑制胰腺星状细胞（PSC）中的细胞外基质（ECM）蛋白的产生，而胰腺星状细胞是抵抗胰腺损伤的经典效应细胞。

更新日期：2018-01-04

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