For the first time, a robust electrochemical sensor to detect the coccidiostat nicarbazin (NCZ) is developed through the green synthesis of Prussian blue cubes from Volvariella volvacea (paddy straw mushroom) extract. Recently, numerous articles were reported about the issue that the prophylactic drugs were injected excessively as a feed additive for fattening the chickens in short period. It is a significant concern that the level of coccidiostat NCZ exceeds the residue limits in the tissues of the meat; mainly, in chicken and eggs. Therefore, it is crucial to develop a sensitive, reproducible and long‐lasting sensor for the real‐time detection of NCZ. Thus, we have generated an electrochemical sensor through the economic screen‐printed carbon electrode (SPCE) modification method. Eco‐friendly Prussian blue cubes are fabricated on the carbon film of SPCE. As a result, the modified electrode showed exceptional electrocatalytic ability towards NCZ and the reduction peak currents are correlated to the concentrations of NCZ. It retains the more extensive working range between 1.25×10⁻⁷ to 1.53×10⁻³ mol L⁻¹, and it possesses a very low limit of detection as well as the appreciable sensitivity. This method is successfully applied to the recognition of NCZ in the samples of chicken meat and eggs.

中文翻译：

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合成结构良好的普鲁士蓝立方体的绿色方法，可有效电催化还原抗原生动物药球虫药尼卡巴嗪

第一次，通过从稻草蘑菇（Volvariella volvacea）提取物制备的普鲁士蓝立方体绿色合成，开发了一种强大的电化学传感器来检测抗球虫药尼卡巴嗪（NCZ）。近来，关于预防性药物作为饲料添加剂过量注射以在短时间内给鸡增脂的问题，报道了许多文章。令人担忧的是，抗球虫药NCZ的水平超过了肉类组织中的残留限量；主要是鸡肉和鸡蛋。因此，开发一种灵敏，可重现且持久的传感器以实时检测NCZ至关重要。因此，我们通过经济的丝网印刷碳电极（SPCE）修改方法生成了一个电化学传感器。在SPCE的碳膜上制造了环保的普鲁士蓝方格。结果，修饰的电极对NCZ显示出优异的电催化能力，并且还原峰值电流与NCZ的浓度相关。它保留了1.25×10之间的更广泛的工作范围^-7至1.53×10 ^-3  mol L ^-1，并且它具有非常低的检测限和明显的灵敏度。该方法已成功应用于鸡肉和鸡蛋样品中NCZ的识别。