An efficient synthesis of 2-fluoroindenones was developed starting from simple o-bromo-2-fluroethenones and aldehydes. This domino reaction involved Knoevenagel condensation and intramolecular Heck coupling cyclization. A variety of 2-fluoroindenones were generated in good to excellent yields.

中文翻译：

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通过Knoevenagel缩合/钯催化的环状结构轻松合成2-氟茚满

从简单的邻-溴-2-氟乙烯酮和醛开始，开发了2-氟茚满的有效合成方法。该多米诺反应涉及Knoevenagel缩合和分子内Heck偶联环化。产生了各种2-氟茚满，其收率很好。