We investigated an Electrolyte-Gated Organic Field-Effect transistor based on poly(N-alkyldiketopyrrolo-pyrrole dithienylthieno[3,2-b]thiophene) as organic semiconductor whose gate electrode was functionalized by electrografting a functional diazonium salt capable to bind an antibody specific to 2,4-dichlorophenoxyacetic acid (2,4-D), an herbicide well-known to be a soil and water pollutant. Molecular docking computations were performed to design the functional diazonium salt to rationalize the antibody capture on the gate surface. Sensing of 2,4-D was performed through a displacement immunoassay. The limit of detection was estimated at around 2.5 fM.

我们研究了基于聚（N-烷基二酮吡咯并吡咯二噻吩并噻吩并[3,2-b]噻吩）作为有机半导体的电解质门控有机场效应晶体管，该晶体管的栅电极通过电接枝能结合抗体特异性抗体的重氮盐而功能化到2,4-二氯苯氧基乙酸（2,4-D），这是众所周知的土壤和水污染物的除草剂。进行分子对接计算以设计功能性重氮盐以合理化抗体在门表面的捕获。通过置换免疫测定法进行2,4-D的检测。检测极限估计为约2.5 fM。