Supramolecular hydrogels for antimicrobial therapy,Chemical Society Reviews

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Supramolecular hydrogels for antimicrobial therapy
Chemical Society Reviews ( IF 40.4 ) Pub Date : 2018-04-26 00:00:00 , DOI: 10.1039/c8cs00128f
Benhui Hu _{1,

2,

3,

4,

5} , Cally Owh _{5,

6} , Pei Lin Chee _{5,

6} , Wan Ru Leow _{1,

2,

3,

4,

5} , Xuan Liu _{7,

8,

9,

10,

11} , Yun-Long Wu _{7,

8,

9,

10,

11} , Peizhi Guo _{2,

11,

12,

13,

14} , Xian Jun Loh _{5,

6} , Xiaodong Chen _{1,

2,

3,

4,

5}

Affiliation

The emergence of drug-resistant microbes has become a threat to global health, and microbial infections severely limit the use of healthcare materials. To achieve efficient antimicrobial therapy, supramolecular hydrogels demonstrate unprecedented advantages in medical applications due to the tunable and reversible nature of their supramolecular interactions and the capability of hydrogels to incorporate various therapeutic agents. Herein, antimicrobial hydrogels are categorized according to their inherent antimicrobial properties or based on their roles in encapsulating antimicrobial materials. Moreover, strategies to further enhance the antimicrobial efficacy of hydrogels are highlighted, such as the incorporation of antifouling agents or the enabling of response towards physiological cues. We envision that supramolecular hydrogels, in combination with modern medical technology and devices, will contribute to the development of efficient and safe systems for antimicrobial therapy.

中文翻译：

超分子水凝胶用于抗菌治疗

耐药微生物的出现已经威胁到全球健康，微生物感染严重限制了医疗保健材料的使用。为了实现有效的抗微生物治疗，超分子水凝胶由于其超分子相互作用的可调性和可逆性以及水凝胶结合各种治疗剂的能力而在医学应用中显示出前所未有的优势。本文中，将抗菌水凝胶根据其固有的抗菌性质或基于其在包封抗菌材料中的作用进行分类。此外，强调了进一步增强水凝胶的抗菌功效的策略，例如掺入防污剂或使对生理线索的反应成为可能。我们设想超分子水凝胶

更新日期：2018-04-26

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