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Parkin mediates mitophagy during beige-to-white fat conversion.
Science Signaling ( IF 6.7 ) Pub Date : 2018-04-24 , DOI: 10.1126/scisignal.aat1082
Shireen A Sarraf 1 , Richard J Youle 1
Affiliation  

In this issue of Science Signaling, Lu et al reveal a role for Parkin-mediated mitophagy in beige-to-white adipocyte transition. In the absence of Parkin, mitochondria in thermogenic beige adipocytes are preserved even after the elimination of cold mimetic stimuli-in contrast to their typical elimination during the white transition.

中文翻译:

帕金在米色至白色脂肪转化过程中介导线粒体。

在《科学信号》(Science Signaling)一期中,Lu等人揭示了帕金介导的线粒体在米色到白色脂肪细胞过渡中的作用。在没有帕金菌的情况下,即使在消除冷模拟刺激后,热生成的米色脂肪细胞中的线粒体也得以保留,这与白色过渡过程中的典型消除相反。
更新日期:2018-04-25
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