The Lancet Commission (Dec 16, 2017, p 2673)¹ on prevention and management of dementia reviews the mounting evidence that hearing loss is a major risk factor for cognitive decline. Crucial information is still absent about the nature of this linkage and what factors might modify the cognitive effect of peripheral hearing loss. Particularly, the potential relevance of central hearing impairment should not be underestimated. As Gill Livingston and colleagues¹ acknowledge, on pathophysiological and neuroanatomical grounds, central auditory processing is likely to be susceptible early in the course of Alzheimer's disease and other dementias.

中文翻译：

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通过针对危险因素预防痴呆

预防和管理痴呆的柳叶刀委员会（2017年12月16日，第2673页）¹审查了越来越多的证据，表明听力下降是认知能力下降的主要危险因素。关于这种联系的性质以及哪些因素可能会改变周围性听力丧失的认知作用，仍然缺乏重要的信息。特别是，不应低估中枢听力障碍的潜在相关性。正如Gill Livingston及其同事¹承认的那样，从病理生理学和神经解剖学的角度来看，中央听觉处理很可能在阿尔茨海默氏病和其他痴呆症的早期很容易受到影响。