N-Acetyl cysteine (NAC) is commonly used as an antioxidant and cytoprotectant, yet a broadly applicable mechanism of these activities has remained elusive. In this issue ofCell Chemical Biology,Ezeriņa et al. (2018)report an alternative mechanism for NAC cytoprotection and antioxidant activity by demonstrating that NAC treatment increases sulfane sulfur production via intermediate H2S generation.

中文翻译：

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S标志着点：将N-乙酰半胱氨酸的抗氧化活性与H2S和硫烷硫物种联系起来

N-乙酰半胱氨酸（NAC）通常用作抗氧化剂和细胞保护剂，但这些活性的广泛应用机制仍然难以捉摸。在本期《细胞化学生物学》中，Ezeriņa等人。（2018）通过证明NAC处理通过中间H2S生成增加了硫磺硫的生成，从而报告了NAC细胞保护和抗氧化活性的另一种机制。