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Cholesterol, cancer, and rebooting a treatment for athlete’s foot
Science Translational Medicine ( IF 15.8 ) Pub Date : 2018-04-18 , DOI: 10.1126/scitranslmed.aat3741 Ngee Kiat Chua 1 , Hudson W. Coates 1 , Andrew J. Brown 1
中文翻译:
胆固醇,癌症和重新治疗脚气
更新日期:2018-04-19
Science Translational Medicine ( IF 15.8 ) Pub Date : 2018-04-18 , DOI: 10.1126/scitranslmed.aat3741 Ngee Kiat Chua 1 , Hudson W. Coates 1 , Andrew J. Brown 1
Affiliation
A key enzyme in cholesterol synthesis is placed firmly on the oncogenic map and demonstrated to be a potential therapeutic target in liver cancer by repurposing a common antifungal agent (Liu et al., this issue).
中文翻译:
胆固醇,癌症和重新治疗脚气
胆固醇合成中的关键酶被牢固地置于致癌基因图上,并通过重新使用常见的抗真菌剂证明其是肝癌的潜在治疗靶标(Liu等,本期)。