Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR,Chemical Communications

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Electrophysiological measurements reveal that a succinyl linker enhances performance of the synthetic chloride channel SCMTR
Chemical Communications ( IF 4.3 ) Pub Date : 2018-04-13 00:00:00 , DOI: 10.1039/c8cc01565a
Farnaz Minooei _{1,

2,

3,

4} , Michael D. Martin _{1,

2,

3,

4} , J. R. Fried _{1,

2,

3,

4} , J. Patrick Brian _{1,

2,

3,

4}

Affiliation

Four variants of a synthetic chloride anion channel composed of dialkyamines linked to a heptapeptide have been studied in different lipid and polymer membranes using electrophysiological techniques. For the first time, the values of conductance states, voltage gating properties, and qualitative state transition frequency were measured in different lipid systems.

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