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Nanoparticles Conjugated with Photocleavable Linkers for the Intracellular Delivery of Biomolecules
Bioconjugate Chemistry ( IF 4.0 ) Pub Date : 2018-04-13 00:00:00 , DOI: 10.1021/acs.bioconjchem.7b00820
Adrián Jiménez-Balsa , Sandra Pinto , Emanuel Quartin , Miguel M. Lino , Vitor Francisco , Lino Ferreira

We report the synthesis and characterization of phototriggerable polymeric nanoparticles (NPs) for the intracellular delivery of small molecules and proteins to modulate cell activity. For that purpose, several photocleavable linkers have been prepared providing diverse functional groups as anchoring points for biomolecules.

中文翻译:

纳米粒子与光可裂解的接头共轭的生物分子的细胞内传递。

我们报告的光触发聚合物纳米颗粒(NPs)的合成和表征细胞内传递的小分子和蛋白质来调节细胞活性。为此目的,已经制备了几种光可裂解的接头,其提供了不同的官能团作为生物分子的锚定点。
更新日期:2018-04-13
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