Facile Synthesis of Chitosan-Coated Silica Nanocapsules via Interfacial Condensation Approach for Sustained Release of Vanillin,Industrial & Engineering Chemistry Research

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Facile Synthesis of Chitosan-Coated Silica Nanocapsules via Interfacial Condensation Approach for Sustained Release of Vanillin
Industrial & Engineering Chemistry Research ( IF 3.8 ) Pub Date : 2018-04-17 , DOI: 10.1021/acs.iecr.8b00217
Qianqian Fan , Jianzhong Ma , Qunna Xu , John Wang ₁ , Yanxiao Ma ₂

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Chitosan-coated silica nanocapsules with a double-shelled structure were crafted using Pluronic F127 as the template via the interfacial condensation approach. The shell of these nanocapsules was composed of an inner layer of silica and an outer layer of chitosan, which was designed for sustained release of vanillin. The average size of nanocapsules was proved to be approximately 37 nm, which could be tunable by varying the usage of chitosan. Significantly, these double-shelled nanocapsules possessed enhanced encapsulation efficiency of 95.5% for vanillin and showed sustained release behaviors. Thermal gravimetric results indicated that the double-shelled structure could endow capsules with improved thermal stability. All of these make them promising candidates for sustained release of small volatile molecules in the industrial field.

中文翻译：

界面缩合法制备香兰素缓释壳聚糖包覆的二氧化硅纳米胶囊

以Pluronic F127为模板，通过界面缩合法制备了具有双壳结构的壳聚糖包被的二氧化硅纳米胶囊。这些纳米胶囊的壳由二氧化硅的内层和壳聚糖的外层组成，其设计用于持续释放香兰素。事实证明，纳米胶囊的平均大小约为37 nm，这可以通过改变壳聚糖的使用来调节。值得注意的是，这些双壳纳米胶囊对香兰素的封装效率提高了95.5％，并表现出持续释放的行为。热重分析结果表明，双壳结构可使胶囊具有更高的热稳定性。所有这些使它们成为工业领域中挥发性小分子持续释放的有希望的候选者。

更新日期：2018-04-17

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