AbstractA glassy carbon electrode was modified with a TiO2-gold nanoparticle hybrid integrated with multi-walled carbon nanotubes in a dihexadecylphosphate film (TiO2-Au NP-MWCNT-DHP/GCE) and applied to amperometric determination of ascorbic acid (AA). The modified sensor displays fast charge transfer and shows an irreversible anodic behavior for AA by cyclic voltammetry. Under optimal experimental conditions and using amperometry at 0.4 V, the analytical curve presented a statistical linear concentration range for AA from 5.0 to 51 μmol L−1, with a limit of detection of 1.2 μmol L−1. The electrode was successfully applied to the determination of AA in pharmaceutical and fruit juice without the need for major pretreatment of samples. Graphical abstractSchematic of a new sensing platform for ascorbic acid (AA). It is based on a glassy carbon electrode (GCE) modified with TiO2-Au nanoparticles integrated into carbon nanotubes in a dihexadecylphosphate film. The sensor was applied to amperometric determination of AA in juice and pharmaceutical samples.

中文翻译：

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用集成到碳纳米管中的 TiO2-金纳米粒子修饰的玻碳电极安培测定抗坏血酸

摘要 在二十六烷基磷酸酯膜（TiO2-Au NP-MWCNT-DHP/GCE）中用TiO2-金纳米颗粒杂化集成多壁碳纳米管对玻碳电极进行修饰，并应用于抗坏血酸（AA）的安培测定。修改后的传感器显示出快速电荷转移，并通过循环伏安法显示出 AA 的不可逆阳极行为。在最佳实验条件下，使用 0.4 V 电流分析法，分析曲线显示 AA 的统计线性浓度范围为 5.0 至 51 μmol L-1，检测限为 1.2 μmol L-1。该电极成功应用于药品和果汁中AA的测定，无需对样品进行大量预处理。抗坏血酸 (AA) 新型传感平台的图形摘要示意图。它基于用 TiO2-Au 纳米粒子改性的玻璃碳电极 (GCE)，该纳米粒子集成到二十六烷基磷酸盐膜中的碳纳米管中。该传感器用于果汁和药物样品中AA的电流法测定。