Ir(III)-Catalyzed Carbocarbation of Alkynes through Undirected Double C–H Bond Activation of Anisoles,Journal of the American Chemical Society

当前位置： X-MOL 学术 › J. Am. Chem. Soc. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Ir(III)-Catalyzed Carbocarbation of Alkynes through Undirected Double C–H Bond Activation of Anisoles
Journal of the American Chemical Society ( IF 14.4 ) Pub Date : 2018-04-11 , DOI: 10.1021/jacs.8b02716
Fedor Romanov-Michailidis ₁ , Benjamin D. Ravetz ₁ , Daniel W. Paley _{1,

2} , Tomislav Rovis ₁

Affiliation

A novel, electron-deficient cyclopentadienyl iridium(III) catalyst enables sequential cleavage of arene C(sp2)-H and methoxy C(sp3)-H bonds of anisoles, generating reactive metalacycles that insert difluoroalkynes to afford chromenes under mild reaction conditions. This transformation is an arylalkylation of an alkyne-a carbocarbation-via a nonchelate-assisted cleavage of two C-H bonds.

中文翻译：

通过苯甲醚的非定向双 C-H 键活化，Ir(III)-催化炔烃的碳碳化反应

一种新型的缺电子环戊二烯基铱 (III) 催化剂能够顺序裂解苯甲醚的芳烃 C(sp2)-H 和甲氧基 C(sp3)-H 键，生成反应性金属环，在温和的反应条件下插入二氟炔烃以提供色烯。这种转化是炔烃的芳烷基化 - 碳碳化 - 通过两个 CH 键的非螯合辅助裂解。

更新日期：2018-04-11

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11