Dictyoneolone (1), a new secosteroid was isolated from a Dictyonella sp. sponge collected from Gageo-do, Korea. Based upon the results of combined spectroscopic analyses, the structure of this compound was determined to possess a highly unusual B/C ring juncture-defused moiety. The configurations of 1 were determined by a combination of proton-proton couplings and NOESY analyses. Dictyoneolone exhibited weak cytotoxicity against the K562 and A549 cancer cell lines.

中文翻译：

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Dictyoneolone，一种来自双歧杆菌属的B / C环连接点分解的类固醇。海绵

Dictyoneolone（1）是一种新的甾体类固醇，是从Dictyonella sp。海绵是从韩国的金乡市收集的。基于组合光谱分析的结果，确定该化合物的结构具有高度不寻常的B / C环接合处-熔化的部分。1的构型是通过质子-质子偶合和NOESY分析的组合来确定的。地克酮对K562和A549癌细胞系的细胞毒性较弱。