Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial.,The Lancet

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Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial.
The Lancet ( IF 98.4 ) Pub Date : 2018-04-21 , DOI: 10.1016/s0140-6736(18)30427-6
Natacha Protopopoff ₁ , Jacklin F Mosha ₂ , Eliud Lukole ₃ , Jacques D Charlwood ₁ , Alexandra Wright ₁ , Charles D Mwalimu ₄ , Alphaxard Manjurano ₂ , Franklin W Mosha ₃ , William Kisinza ₅ , Immo Kleinschmidt ₆ , Mark Rowland ₁

Affiliation

Progress in malaria control is under threat by wide-scale insecticide resistance in malaria vectors. Two recent vector control products have been developed: a long-lasting insecticidal net that incorporates a synergist piperonyl butoxide (PBO) and a long-lasting indoor residual spraying formulation of the insecticide pirimiphos-methyl. We evaluated the effectiveness of PBO long-lasting insecticidal nets versus standard long-lasting insecticidal nets as single interventions and in combination with the indoor residual spraying of pirimiphos-methyl.

中文翻译：

长效胡椒基丁醚处理的杀虫网和室内滞留喷雾干预措施（单独或联合）对抗拟除虫菊酯抗性蚊子传播的疟疾的有效性：一项集群、随机对照、二乘二析因设计试验。

疟疾控制方面的进展正受到疟疾病媒大规模杀虫剂耐药性的威胁。最近开发了两种病媒控制产品：一种含有增效剂胡椒基丁醚 (PBO) 的长效杀虫网和一种长效室内滞留喷洒杀虫剂甲基嘧啶磷的配方。我们评估了 PBO 长效杀虫蚊帐与标准长效杀虫蚊帐作为单一干预措施以及与甲基嘧啶磷室内滞留喷洒相结合的效果。

更新日期：2018-04-20

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