One-dimensional nanostructure materials offer opportunities for improving performance of electrochemical sensors. In this work, vertically ZnO nanorods (ZNRs) sensitized with gold nanoparticles (GNPs) were designed and fabricated onto indium tin oxide coated polyethylene terephthalate (ITO/PET) film for dopamine sensing. ZNRs that helpful for electric signal collecting by providing electron transfer pathways were electrodeposited on ITO/PET film firstly. Then GNPs that possess excellent electrocatalytic activity toward target were decorated onto ZNRs via potentiodynamic electrodeposition. These gold nanoparticles sensitized ZnO nanorods arrays (GNPs/ZNRs) combine the advantages of GNPs and ZNRs, thus providing chance to develop electrochemical sensors with ultrahigh sensitivity and excellent selectivity. Several important nervous system diseases (such as Parkinson's disease, schizophrenia, senile dementia, AIDS, et al.) have proved to be associated with dysfunctions of dopamine system. So, the detection of dopamine becomes essential in clinical medical practice and nerve physiology study. When used for dopamine sensing, the fabricated electrochemical sensor shows two linear dynamic ranges (0.01–20 μM and 50–1000 μM) toward dopamine. Moreover, this proposed electrochemical sensor has been successfully applied to the determination of dopamine in human urine with satisfied recoveries (95.3% to 111.3%) and precision (1.1% to 8.4% of RSD).

中文翻译：

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金纳米粒子敏化的多巴胺电化学传感的ZnO纳米棒阵列。

一维纳米结构材料为改善电化学传感器的性能提供了机会。在这项工作中，设计了用金纳米颗粒（GNP）敏化的垂直ZnO纳米棒（ZNR），并将其制造在氧化铟锡涂层的聚对苯二甲酸乙二醇酯（ITO / PET）膜上，用于多巴胺感测。首先通过在ITO / PET膜上电沉积通过提供电子传递途径而有助于电信号收集的ZNR。然后，通过电位电沉积将对目标具有优异电催化活性的GNPs修饰到ZNRs上。这些金纳米颗粒敏化的ZnO纳米棒阵列（GNPs / ZNRs）结合了GNPs和ZNRs的优点，从而为开发具有超高灵敏度和出色选择性的电化学传感器提供了机会。几种重要的神经系统疾病（如帕金森氏病，精神分裂症，老年性痴呆，艾滋病等）已证明与多巴胺系统功能障碍有关。因此，多巴胺的检测在临床医学实践和神经生理学研究中变得至关重要。当用于多巴胺传感时，制成的电化学传感器对多巴胺表现出两个线性动态范围（0.01–20μM和50–1000μM）。此外，该拟议的电化学传感器已成功地用于测定人尿中的多巴胺，其回收率令人满意（RSD为95.3％至111.3％）和精密度（RSD为1.1％至8.4％）。多巴胺的检测在临床医学实践和神经生理学研究中变得至关重要。当用于多巴胺传感时，制成的电化学传感器对多巴胺表现出两个线性动态范围（0.01–20μM和50–1000μM）。此外，该拟议的电化学传感器已成功地用于测定人尿中的多巴胺，其回收率令人满意（RSD为95.3％至111.3％）和精密度（RSD为1.1％至8.4％）。多巴胺的检测在临床医学实践和神经生理学研究中变得至关重要。当用于多巴胺传感时，制成的电化学传感器对多巴胺表现出两个线性动态范围（0.01–20μM和50–1000μM）。此外，该拟议的电化学传感器已成功地用于测定人尿中的多巴胺，其回收率令人满意（RSD为95.3％至111.3％）和精密度（RSD为1.1％至8.4％）。