A reliable protocol for converting 1,4-diiodo-2,3,5,6-tetrafluorobenzene into 1-(hetero)aryl-4-iodo-2,3,5,6-tetrafluorobenzene derivatives has been lacking in the literature. We have identified optimal conditions to achieve this conversion in good yields and have minimized formation of the bis-coupling product. The newly identified protocol involving the use of a syringe pump has been extended to other symmetrical diiodo(hetero)arenes.

中文翻译：

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对称二碘（杂）芳烃的高效Suzuki-Miyaura单芳基化

文献中缺乏将1，4-二碘-2，3，5，6-四氟苯转化成1-（杂）芳基-4-碘-2，3，5，6-四氟苯衍生物的可靠方案。我们已经确定了最佳条件，可以实现高收率的这种转化，并最大程度地减少了双偶合产物的形成。新近确定的涉及使用注射泵的方案已扩展到其他对称的二碘（杂）芳烃。