A general strategy for the preparation of functionalized imidazole- and pyrazine-appended porphyrins involving in situ generation of 2,3-diaminoporphyrin and its subsequent interaction with carbonyl compounds was developed. The tuning of the selectivity of the reaction between 2,3-diaminoporphyrin and aromatic aldehyde by variation of the reaction conditions was demonstrated. Efficient pathways are revealed allowing selective preparation of different types of heterocycle-appended porphyrins, namely arenepyrazino-, 2-arylimidazo- and 2,3-diarylpyrazino-derivatives.

中文翻译：

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回顾2，3-二氨基卟啉：杂环附加卟啉的关键合成子

开发了一种制备功能化咪唑和吡嗪的卟啉的一般策略，该方法涉及就地生成2,3-二氨基卟啉及其随后与羰基化合物的相互作用。证明了通过改变反应条件来调节2，3-二氨基卟啉与芳族醛之间的反应的选择性。揭示了允许选择性制备不同类型的杂环附加卟啉的有效途径，即卟啉-，2-芳基咪唑-和2,3-二芳基吡嗪-衍生物。