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Synthesis of benzyl halide derivatives of spirohydantoins via [2+2+2] cyclotrimerization reaction
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-04-07 , DOI: 10.1016/j.tetlet.2018.04.012
Sanbasivarao Kotha , Gaddamedi Sreevani

Generally, synthesis of hydantoin derivatives involve use of carbonyl compounds which in turn require multistep synthesis. Here, we report a new approach to assemble spirohydantoins via [2+2+2] cyclotrimerization reaction using commercially available, inexpensive hydantoin as a starting material.



中文翻译:

通过[2 + 2 + 2]环三聚反应合成螺乙内酰脲的苄基卤化物衍生物

通常,乙内酰脲衍生物的合成涉及羰基化合物的使用,而羰基化合物又需要多步合成。在这里,我们报告了一种新方法,可使用市售的廉价乙内酰脲作为起始原料,通过[2 + 2 + 2]环三聚反应组装螺乙内酰脲。

更新日期:2018-04-07
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