This study investigated the effects and fate of CIP on anaerobic sludge over a wide range of concentrations (0.05–50 mg/L), and 0.5–50 mg/L significantly inhibited organic removal and methanogenic activity, increased volatile fatty acids accumulation and low molecular weight soluble microbial products (SMPs), including p-cresol and nitrogen-containing compounds. Although microbial communities exposed to CIP did not differ significantly from the control in species diversity indices, Syntrophobacter and Methanothrix associated with acetogenesis and acetoclastic methanogenesis, respectively, were underrepresented in the CIP-exposed communities. Our study advances understanding of how environmentally relevant concentrations of CIP disrupts anaerobic digestion, which has important implications for anaerobic engineered systems treating CIP-bearing waste streams.

这项研究调查了在不同浓度（0.05–50 mg / L）下CIP对厌氧污泥的影响和结局，而0.5–50 mg / L则显着抑制了有机物去除和产甲烷活性，增加了挥发性脂肪酸的积累和低分子重量较重的微生物产品（SMP），包括对甲酚和含氮化合物。尽管暴露于CIP的微生物群落在物种多样性指数上与对照没有显着差异，但是滑膜细菌和甲烷菌在CIP暴露的社区中，分别与乙酰化和乙酰破伤性甲烷生成相关的代表性不足。我们的研究提高了对与环境相关的CIP浓度如何破坏厌氧消化的理解，这对于处理含CIP废物流的厌氧工程系统具有重要意义。