Synthetic Approaches to New Drugs Approved During 2016,Journal of Medicinal Chemistry

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Synthetic Approaches to New Drugs Approved During 2016
Journal of Medicinal Chemistry ( IF 6.8 ) Pub Date : 2018-04-05 00:00:00 , DOI: 10.1021/acs.jmedchem.8b00260
Andrew C. Flick ₁ , Hong X. Ding ₂ , Carolyn A. Leverett ₁ , Sarah J. Fink ₃ , Christopher J. O’Donnell ₁

Affiliation

New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 19 new chemical entities that were approved for the first time in 2016.

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