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Fighting leukemia with “duel”-targeted therapy
Science Translational Medicine ( IF 15.8 ) Pub Date : 2018-04-04 , DOI: 10.1126/scitranslmed.aat3887 Tríona Ní Chonghaile 1
中文翻译:
以“决斗”为目标的抗击白血病
更新日期:2018-04-05
Science Translational Medicine ( IF 15.8 ) Pub Date : 2018-04-04 , DOI: 10.1126/scitranslmed.aat3887 Tríona Ní Chonghaile 1
Affiliation
Combining BCL-2 inhibitor venetoclax with monoclonal CD20 antibody rituximab greatly enhances progression-free survival compared with bendamustine-rituximab in a phase 3 trial of relapsed or refractory chronic lymphocytic leukemia patients.
中文翻译:
以“决斗”为目标的抗击白血病
与苯达莫司汀-利妥昔单抗的复发或难治性慢性淋巴细胞白血病患者的3期试验相比,将BCL-2抑制剂venetoclax与单克隆CD20抗体利妥昔单抗联合使用可大大提高无进展生存期。