AbstractSmart hydrogel materials are a popular topic of investigation because they have the potential to be used as smart drug carriers and soft actuators. Hydrogel materials showing responsiveness to logic gate-type stimuli are of special interest because their responsiveness can be regulated more accurately than that of common stimuli-responsive materials. In this study, poly(N-isopropylacrylamide) nanogels containing catechol substituents in their polymer network structure were prepared via precipitation polymerization. The prepared nanogels showed AND-type logic gate thermal aggregation behavior. The possible use of this logic gate-type smart nanogel aggregating system was investigated in a smart valve system.Poly(N-isopropylacrylamide) nanogels having catechol substituents were prepared. It was found that the aqueous dispersion of the nanogel showed thermal aggregation responding to body temperature only in the case that Fe3+ was mixed and then pH increased. It can be said that this thermal aggregation system of the nanogel is one kind of AND-type logic gate aggregation system. We also showed the possibility that this AND-type nanogel aggregation can be used as a smart valve system regulating water flow.

中文翻译：

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具有响应体温的邻苯二酚取代基的聚（N-异丙基丙烯酰胺）纳米凝胶的逻辑门聚合

摘要智能水凝胶材料是一个热门的研究课题，因为它们具有用作智能药物载体和软致动器的潜力。对逻辑门型刺激表现出响应性的水凝胶材料特别令人感兴趣，因为它们的响应性可以比普通刺激响应性材料更准确地调节。在这项研究中，通过沉淀聚合制备了在其聚合物网络结构中含有儿茶酚取代基的聚（N-异丙基丙烯酰胺）纳米凝胶。制备的纳米凝胶表现出与型逻辑门热聚集行为。研究了这种逻辑门型智能纳米凝胶聚集系统在智能阀系统中的可能用途。制备了具有邻苯二酚取代基的聚（N-异丙基丙烯酰胺）纳米凝胶。发现纳米凝胶的水分散体仅在混合Fe3+然后pH升高的情况下才表现出响应体温的热聚集。可以说，纳米凝胶的这种热聚集系统是一种AND型逻辑门聚集系统。我们还展示了这种 AND 型纳米凝胶聚集体可用作调节水流的智能阀门系统的可能性。