A convergent formal [4 + 2] cycloaddition of 1,6-diynes and benzyl azides: construction of spiro-polyheterocycles†,Organic & Biomolecular Chemistry

当前位置： X-MOL 学术 › Org. Biomol. Chem. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

A convergent formal [4 + 2] cycloaddition of 1,6-diynes and benzyl azides: construction of spiro-polyheterocycles†
Organic & Biomolecular Chemistry ( IF 2.9 ) Pub Date : 2018-04-04 00:00:00 , DOI: 10.1039/c8ob00735g
Ming Bao _{1,

2,

3,

4,

5} , Wei Lu _{1,

2,

3,

4,

5} , Han Su _{1,

2,

3,

4,

5} , Lihua Qiu _{1,

2,

3,

4,

5} , Xinfang Xu _{1,

2,

3,

4,

5}

Affiliation

A convergent formal [4 + 2] cycloaddition reaction for the construction of structurally appealing spiro-tetrahydroquinolines has been developed, in which, a one-pot reaction is established for the in situ generation of two reagents, a cyclic alkyne and an N-aryliminium ion, from the corresponding precursors in the presence of an Au-catalyst and Brønsted acid, respectively.

中文翻译：

1,6-二炔和苄基叠氮化物的收敛形式[4 + 2]环加成：螺-多杂环的构建†

已经开发出一种收敛的正式[4 + 2]环加成反应，用于构建结构吸引人的螺-四氢喹啉，其中建立了一个一锅反应，可就地生成两种试剂，环状炔烃和N-芳基亚胺离子，分别在金催化剂和布朗斯台德酸的存在下从相应的前体中分离出来。

更新日期：2018-04-04

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11