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Facile synthesis of diphenylmethyl esters from 2-diphenylmethoxypyridine using catalytic boron trifluoride·diethyl etherate
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2018-04-03 , DOI: 10.1016/j.tetlet.2018.04.002
Minh Thanh La , Hee-Kwon Kim

A practical method for the direct preparation of diphenylmethyl (DPM) esters from 2-diphenylmethoxypyridine is described. The reaction was readily performed in the presence of a catalytic amount of boron trifluoride-diethyl etherate at room temperature. Using this reaction protocol, various carboxylic acids were converted to DPM esters with high yields. This method is highly effective for the protection of carboxylic acids and the synthesis of DPM esters, and offers a promising approach for facile esterification of a variety of carboxylic acids.



中文翻译:

用三氟化硼·二乙醚催化从2-二苯基甲氧基吡啶容易地合成二苯基甲酯

描述了一种由2-二苯基甲氧基吡啶直接制备二苯基甲基(DPM)酯的实用方法。该反应在室温下在催化量的三氟化硼-二乙基醚化物的存在下容易地进行。使用该反应方案,可以将各种羧酸高产率地转化为DPM酯。该方法对于保护羧酸和DPM酯的合成非常有效,并且为各种羧酸的简便酯化提供了一种有希望的方法。

更新日期:2018-04-03
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