Currently there is a lack of inexpensive, easy-to-use technology to evaluate human exposure to environmental chemicals, including polycyclic aromatic hydrocarbons (PAHs). This is the first study in which silicone wristbands were deployed alongside two traditional personal PAH exposure assessment methods: active air monitoring with samplers (i.e., polyurethane foam (PUF) and filter) housed in backpacks, and biological sampling with urine. We demonstrate that wristbands worn for 48 h in a non-occupational setting recover semivolatile PAHs, and we compare levels of PAHs in wristbands to PAHs in PUFs-filters and to hydroxy-PAH (OH-PAH) biomarkers in urine. We deployed all samplers simultaneously for 48 h on 22 pregnant women in an established urban birth cohort. Each woman provided one spot urine sample at the end of the 48-h period. Wristbands recovered PAHs with similar detection frequencies to PUFs-filters. Of the 62 PAHs tested for in the 22 wristbands, 51 PAHs were detected in at least one wristband. In this cohort of pregnant women, we found more significant correlations between OH-PAHs and PAHs in wristbands than between OH-PAHs and PAHs in PUFs-filters. Only two comparisons between PAHs in PUFs-filters and OH-PAHs correlated significantly (r_s = 0.53 and p = 0.01; r_s = 0.44 and p = 0.04), whereas six comparisons between PAHs in wristbands and OH-PAHs correlated significantly (r_s = 0.44 to 0.76 and p = 0.04 to <0.0001). These results support the utility of wristbands as a biologically relevant exposure assessment tool which can be easily integrated into environmental health studies.

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当前，缺乏廉价，易于使用的技术来评估人体对环境化学品（包括多环芳烃（PAH））的暴露程度。这是首次将硅胶腕带与两种传统的个人PAH暴露评估方法一起部署的研究：使用装在背包中的采样器（即，聚氨酯泡沫（PUF）和过滤器）进行主动空气监测，以及对尿液进行生物采样。我们证明了在非职业环境中佩戴腕带48小时可以恢复半挥发性PAH，并且我们将腕带中的PAHs与PUFs过滤器中的PAHs以及尿液中的羟基-PAH（OH-PAH）生物标志物进行了比较。我们在一个既定的城市出生队列中，对22名孕妇同时部署了所有采样器48小时。每位妇女在48小时结束时提供了一份尿样。腕带恢复的PAH具有与PUF滤波器相似的检测频率。在22个腕带中测试的62个PAH中，至少有一个腕带中检测到51个PAH。在这组孕妇中，我们发现腕带中的OH-PAH和PAH之间的相关性比PUF过滤器中的OH-PAH和PAH之间的相关性更大。PUF过滤器中的PAH和OH-PAH之间只有两个比较具有显着的相关性（r _s  = 0.53，p  = 0.01；r _s  = 0.44和p  = 0.04），而腕带中的PAHs和OH-PAHs之间的六次比较显着相关（r _s  = 0.44至0.76和p  = 0.04至<0.0001）。这些结果支持了腕带作为生物学相关的暴露评估工具的实用性，可以很容易地整合到环境健康研究中。

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