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Total Synthesis of (±)-Minfiensine via a Formal [3+2] Cycloaddition
Journal of Natural Products ( IF 5.1 ) Pub Date : 2018-03-30 00:00:00 , DOI: 10.1021/acs.jnatprod.7b00873
Chao Zhang 1, 2 , Wenzhi Ji 1 , Yahu A. Liu 3 , Chun Song 2 , Xuebin Liao 1
Affiliation  

(±)-Minfiensine (1) was synthesized in 10 steps in 26% overall yield with the 1,2,3,4-tetrahydro-9a,4a-iminoethanocarbazole core constructed through a [3+2] cycloaddition reaction between indole and an azaoxyallylic cation.

中文翻译:

通过正式的[3 + 2]环加成反应全合成(±)-Minfiensine

(±)-Minfiensine(1)以10个步骤合成,总产率为26%,其中的1,2,3,4-四氢-9a,4a-亚氨基乙基氨基咔唑核是通过吲哚和环戊二烯之间的[3 + 2]环加成反应构建的氮氧基烯丙基阳离子。
更新日期:2018-03-30
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